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nonylphenol ethoxylate toxicity

Lifespan was reduced by NP-9 in P0 and F1, but the effect was greater in the parents. code toxicity oral rats ld50: 1600mg/kg 1A or 1B and/or an entry in the Candidate list. Ethoxylated nonylphenol caused deficits in locomotor behavior in the nematode. NONYL PHENOL ETHOXYLATED (R22-R41-R51/53) C&L Inventory . Toxicity of Nonylphenol Ethoxylate Metabolites Many countries, large corporations and scientific entities have classified NPE metabolites as toxic. Toxicity Ecology - water : Very toxic to aquatic life with long lasting effects. Spic and Span Multi-Surface and Floor Cleaner Environmental Working Group The cleaner contains nonylphenol ethoxylate, which, when it breaks down to nonylphenol… Nonyl-phenol ethoxylates have much narrower homologue distributions than alcohol ethoxylates (ICI datasheet for Synperonic NP surfactants). chemistry properties, toxicity and analytical methods in various matrices. 12.2. Acute toxicity tests using nonylphenol (NP), nonylphenol monoethoxylate (NP1EO), and nonylphenol diethoxylate (NP2EO) were conducted using the single chemicals and as binary and tertiary mixtures. Persistence and degradability h.s. It originates principally from the degradation of nonylphenol ethoxylates which are widely used as industrial surfactants. R – This substance was identified as toxic to reproduction (i.e. Toxic to Reproduction (R) – Recognised as toxic to reproduction: comes from a harmonised C&L classifying the substance as Carc. 2 ... Nonylphenol and nonylphenol ethoxylates are toxic to aquatic organisms, and the breakdown products of nonylphenol ethoxylates (NP and shorter-chained ethoxylates) are more toxic and more persistent than their parent chemicals. Due to its harmful effects on the environment, use and production of nonylphenol has been banned in European 2. NONYL PHENOL ETHOXYLATED Safety Data Sheet www.lobachemie.com 09/04/2015 6/10 Aspiration hazard : Not classified Potential adverse human health effects and symptoms: Harmful if swallowed. The agency added nonylphenol (NP) to the list in 2014 based on toxicity to aquatic organisms as it “is even more toxic to aquatic organisms than short-chain NPEs.” NP-9 induced non-monotonic responses in growth and neurotoxicity markers. formula c9h19c6h4(och2ch2)noh mol wt. Three phenolic compounds were evaluated for their toxicity to the freshwater species Pimephales promelas (fathead minnow) and Ceriodaphnia dubia. nonylphenol ethoxylate (NPE) making up more than 80% of the alkylphenol ethoxylate market in North America. De la Parra-Guerra A(1), Stürzenbaum S(2), Olivero-Verbel J(3). Intergenerational toxicity of nonylphenol ethoxylate (NP-9) in Caenorhabditis elegans. SECTION 12: Ecological information 12.1. Nonylphenol is a toxic xenobiotic compound classified as an endocrine disrupter capable of interfering with the hormonal system of numerous organisms. nonylphenol ethoxylate product identification cas no 26027-38-3 einecs no. Nonylphenol ethoxylates re … Potentially toxic to reproduction: comes from a harmonised C&L classifying the substance as suspected toxic to reproduction Repr. C&L Inventory . 880 million pounds (4 mio metric tonnes) of alkyl phenol ethoxylates are used annually throughout the world. classified in reproductive toxicity categories 1A or 1B) ... NONYL PHENOL ETHOXYLATE. Author information: (1)Environmental and Computational Chemistry Group, University of Cartagena, Cartagena, Colombia. nonyl phenol reacted with ethylene oxide. Canada classified NPE metabolites as toxic, as they are “entering the environment in a quantity or concentration or under conditions that have or may have an immediate or long-term As a degradation product of ethoxylated alkylphenols, nonylphenol presents a higher degree of reactivity than its precursor. 80-85% are sold as nonylphenol ethoxylate (NPE), over 15% as octylphenol ethoxylate, and 1% each as Hormonal system of numerous organisms are widely used as industrial surfactants … R – substance! Toxicity of nonylphenol ethoxylates re … R – This substance was identified toxic! Was reduced by NP-9 in P0 and F1, but the effect was greater in the Candidate list nematode. Suspected toxic to aquatic life with long lasting effects: comes from a C! 2 ), Stürzenbaum S ( 2 ), Olivero-Verbel J ( 3 ) identified! Nonyl-Phenol ethoxylates have much narrower homologue distributions than alcohol ethoxylates ( ICI datasheet for Synperonic NP surfactants ) pounds 4. 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